I think the easiest application to help people understand what quorum sensing is and why it's important to study is to tell them that if we could make the bacteria either deaf or mute, we could create new antibiotics.
In my lab, we are always thinking about how cells, bacterial cells, can talk to each other and then organize themselves into enormous groups that function in unison.
Most bacteria aren't bad. We breathe and eat and ingest gobs of bacteria every single moment of our lives. Our food is covered in bacteria. And you're breathing in bacteria all the time, and you mostly don't get sick.
We've all been sick; we're all afraid of infection. I think the easiest application to help people understand what quorum sensing is and why it's important to study is to tell them that if we could make the bacteria either deaf or mute, we could create new antibiotics.
As a kid, I loved doing puzzles, solving riddles, and reading mystery books. I also loved animals and always had pets.
I remember the day we found the gene for the inter-species signaling molecule like it was yesterday. We got the gene, and we plugged it into a database. And we immediately saw that this gene was in an amazing number of species of bacteria. It was a huge moment of realization.