I would amputate my toes to work with Lars von Trier again.

'50/50' is a comedy. I shouldn't say it's a buddy comedy because it's not farcical, and it's based on a true story, but it's viewing that experience through a very truthful lens of humour.

There's a lot of wisdom that my dad and my grandparents and my uncle have been able to impart on me, and what I've treasured the most is I've seen examples in my life of people embracing their creativity, not feeling insecure about their artistic inclinations.

My first time I directed a play was 'No Exit,' a play set in a subway.

Sometimes people are like, 'Do you want to play strong women?' I don't have to play strong women in order to feel like a strong woman myself, but I do feel it's important to play characters that are complex and interesting and believable.