By combining chemical, biochemical and physical techniques, it has thus become possible to investigate the nature of enzymic catalysis in a novel manner, complementary to the other approaches which have developed over the same period.
Part of my childhood was spent in Sydney and part in rural New South Wales, at Armidale.
I was born on 7 September 1917 at Sydney in Australia. My father was English-born and a graduate of Oxford; my mother, born Hilda Eipper, was descended from a German minister of religion who settled in New South Wales in 1832. I was the second of four children.
In 1962, Popjak and I left the service of the Medical Research Council and became co-directors of the Milstead Laboratory of Chemical Enzymology set up by Shell Research Ltd.
At the National Institute for Medical Research, I came into contact with biological scientists and formed collaborative projects with several of them. In particular, George Popjak and I shared an interest in cholesterol.
Throughout my scientific career, my wife has been my most constant collaborator. Her experimental skill made major contributions to the work; she has eased for me beyond measure the difficulties of communication that accompany deafness; her encouragement and fortitude have been my strongest supports.
