No matter what monks in their Himalayan caves or philosophers in their ivory towers say, for the capitalist juggernaut, happiness is pleasure. Period. With each passing year our tolerance for unpleasant sensations decreases, and our craving for pleasant sensations increases. Both scientific research and economic activity are geared to that end, each year producing better painkillers, new ice-cream flavours, more comfortable mattresses, and more addictive games for our smartphones, so that we will not suffer a single boring moment while waiting for the bus. All this is hardly enough, of course. Since Homo sapiens was not adapted by evolution to experience constant pleasure, if that is what humankind nevertheless wants, ice cream and smartphone games will not do. It will be necessary to change our biochemistry and re-engineer our bodies and minds. So we are working on that. You may debate whether it is good or bad, but it seems that the second great project of the twenty-first century – to ensure global happiness – will involve re-engineering Homo sapiens so that it can enjoy everlasting pleasure.